Whether a singular verb or a plural verb should be used for two pounds of pork or two glasses of milk depends on the sentence's singular or plural meaning.
e.g.
Two pounds of pork is what's needed for today's cooking.
Two glasses of milk every day is the key to his good health.
Two pounds of pork are stored in the freezer.
Two glasses of milk were served at the breakfast.
I think Glotynn's explanation sounds very reasonable. Therefore, we should choose "is" when we say "two pounds of pork is not too much for me." Is it right?